Genome Editing (CRISPR/Cas9) in Plant Disease Management: Challenges and Future Prospects
Kallol Das 1, A-B,D,F
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College of Agriculture and Life Sciences, Kyungpook National University, Daegu, South Korea, Korea (South)
Ministry of Food and Agriculture, Plant Protection and Regulatory Services Directorate, Ashanti 23321, Ghana, Ghana
Plant Disease Clinic and Bank of Pathogens, Institute of Plant Protection-National Research Institute, Poznan, Poland, Poland
Rice Farming System Division, Bangladesh Rice Research Institute, Regional Station, Gopalganj, Bangladesh, Bangladesh
Department of Plant Pathology, Sher-e-Bangla Agricultural University, Sher-e-Bangla Nagar, Dhaka-1207, Bangladesh, Bangladesh
A - Research concept and design; B - Collection and/or assembly of data; C - Data analysis and interpretation; D - Writing the article; E - Critical revision of the article; F - Final approval of article
Kallol Das   

College of Agriculture and Life Sciences, Kyungpook National University, Daegu, South Korea, 80, Daehak-ro, 41566, Daegu, Korea (South)
Submission date: 2023-02-21
Acceptance date: 2023-04-05
Online publication date: 2023-04-19
  • • There will be at least 9.8 billion people in the world by 2050, and they will need a steadily increasing amount of food.
  • • CRISPR/Cas9 gene editing technique in plant pathosystems requires knowledge of its mechanisms and natural systems.
  • • Global researchers developed the CRISPR/Cas9 microbial adaptive immune system.
The field of plant pathology has adopted targeted genome editing technology as one of its most crucial and effective genetic tools. Due to its simplicity, effectiveness, versatility, CRISPR together with CRISPR-associated proteins found in an adaptive immune system of prokaryotes have recently attracted the interest of the scientific world. Plant disease resistance must be genetically improved for sustainable agriculture. Plant biology and biotechnology have been transformed by genome editing, which makes it possible to perform precise and targeted genome modifications. Editing offers a fresh approach by genetically enhancing plant disease resistance and quickening resistance through breeding. It is simpler to plan and implement, has a greater success rate, is more adaptable and less expensive than other genome editing methods. Importantly CRISPR/Cas9 has recently surpassed plant science as well as plant disease. After years of research, scientists are currently modifying and rewriting genomes to create crop plants which are immune to particular pests and diseases. The main topics of this review are current developments in plant protection using CRISPR/Cas9 technology in model plants and commodities in response to viral, fungal, and bacterial infections, as well as potential applications and difficulties of numerous promising CRISPR/Cas9-adapted approaches.
The authors have declared that no conflict of interests exist.