Studies on seed storage were conducted at seed processing and storage section of the Institute of Agricultural Research and Training, Obafemi Awolowo University, Moor Plantation, Ibadan Nigeria in 2007 and 2008, to evaluate High protein maize (HPM) seed for resistance/tolerance to storage insect pest, and assess the resultant effect of seed treatment chemicals on its germination potential. Seeds of HPM variety (ART-98-SW1) and Quality protein maize (QPM) variety (ILE-1-OB) and two varieties of field corn (SUWAN-1-SR and TZPB-SRW) were treated with chemicals, namely FitscophosTM, Actellic 25 ECTM, Apron StarTM and combination of Actellic 25 EC and Fitscophos before storing them under controlled environment for six months. The results show that HPM, QPM and field corn require storage chemicals for effective storage, but both QPM and HPM varieties were significantly damaged by storage insect pests compared to field corn varieties regardless of the chemical used. Apron Star effectively reduced infestation by insect pests, but it may bring about significant reduction in seed viability if used for long term storage. Combination of Actellic 25 EC and Fitscophos successfully reduced infestation by insect pests without significant injurious effect on seed viability. Breeding programmes for resistance to storage pests is recommended while long term effects of Apron Star on seed viability needs to be investigated before recommending it for use in HPM/QPM maize varieties.