ORIGINAL ARTICLE
Enhancing Toxicity of Pyrethroids by Oxidase and Esterase Inhibitors in Spodoptera littoralis (Boisd.) Larvae
 
 
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Department Insect Population Toxicology, Central Agricultural Pesticides Laboratory, Agriculture Research Center, Dokki, Giza, Egypt, Egypt
 
 
A - Research concept and design; B - Collection and/or assembly of data; C - Data analysis and interpretation; D - Writing the article; E - Critical revision of the article; F - Final approval of article
 
 
Submission date: 2023-05-22
 
 
Acceptance date: 2023-10-18
 
 
Online publication date: 2023-10-26
 
 
Corresponding author
Seham Mansour Ismail   

Department Insect Population Toxicology, Central Agricultural Pesticides Laboratory, Agriculture Research Center, Dokki, Giza, Egypt, Dokki, 21500, Giza, Egypt
 
 
 
HIGHLIGHTS
  • ► Piperonyl butoxide (PB) or organophosphorus compounds (OPs) synergised with pyrethroid insecticides against cotton leafworm larvae both in vivo. ► Significantly increased synergism is shown with PB + OPs for pyrethroid insecticides.
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ABSTRACT
Although pyrethroids are increasingly being used to control a number of agricultural insect pests, especially the cotton leafworm, Spodoptera littoralis (Boisd.), pyrethroid resistance is a major obstacle limiting effective control. Aiming to maintain the effectiveness of pyrethroids in managing pests, a study was undertaken to evaluate the effectiveness of oxidase and esterase inhibitors for synergizing pyrethroids in S. littoralis larvae. In comparison to the insecticide-susceptible strain (L-SS) of S. littoralis, the resistance ratio (RR) in the field population (F-RS) was determined to be 271.43-fold for cypermethrin. An esterase inhibitor such as profenofos significantly increased larval susceptibility to cypermethrin in the F-RS strain, with a synergism ratio (SR) of up to 192.57 -fold. Significant inhibition of esterase by profenofos in the F-RS strain was found in vivo. On the other hand, in the F-RS strain of S. littoralis, an oxidase inhibitor such as piperonyl butoxide (PB) had a slight effect on the toxicity of cypermethrin and thus adding PB to cypermethrin is not a solution for pyrethroid resistance. Thus, modifying the toxicity of cypermethrin by mixing it with organophosphorous compounds (OPs) led to an increase in its toxicity and a reduction in the S. littoralis population, and which is a successful strategy for managing pyrethroid resistance.
CONFLICT OF INTEREST
The authors have declared that no conflict of interests exist.
eISSN:1899-007X
ISSN:1427-4345
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