ORIGINAL ARTICLE
A comparative study of the antifungal activity of silver nanoparticles prepared from Moringa oleifera and Spirulina platensis extracts against Aspergillus parasiticus isolated from Egyptian wheat grains
1
Botany and Microbiology, Faculty of Science, University of Damietta, New Damietta, Egypt
A - Research concept and design; B - Collection and/or assembly of data; C - Data analysis and interpretation; D - Writing the article; E - Critical revision of the article; F - Final approval of article
Submission date: 2024-06-15
Acceptance date: 2024-08-20
Online publication date: 2025-09-17
Corresponding author
Zakaria Awad Baka
Botany and Microbiology, Faculty of Science, University of Damietta, New Damietta, Egypt
Botany and Microbiology, Faculty of Science, University of Damietta, New Damietta, Egypt
HIGHLIGHTS
- A. parasiticus was morphologically and molecularly identified
- AgNPs were biosynthesized from M. oleifera and S. platensis extracts
- Phenolic compounds in S. platensis were higher than those in M. oleifera.
- A. parasiticus isolates showed higher amounts of AFB1 than AFB2
- The antifungal activity of AgNPs was studied against the fungus by SEM and TEM
KEYWORDS
TOPICS
ABSTRACT
This work aimed to investigate the in vitro antifungal capability of silver nanoparticles
(AgNPs) that were biosynthesized from extracts of two bioagents (Moringa oleifera and
Spirulina platensis) against Aspergillus parasiticus attained from Egyptian wheat grains.
Aspergillus parasiticus exhibited the most established species, additionally, the metabolite of isolate
3 generated a better quantity of Aflatoxin B1 (899.8 μg · l-1). AgNPs prepared from
bioagent extracts inhibited the fungal mycelia and spore germination, even though
S. platensis extract was more potent. The extract of S. platensis confirmed 22 phenolic compounds,
with epicatechin (3455.9 μg · g-1 DW) recording the largest quantity. In evaluation,
M. oleifera leaf extract revealed the existence of 16 phenolic compounds, with chlorogenic
acid verifying the very best degree (3250.9 μg · g-1 DW). Fungal mycelia treated with
10% AgNPs showed intense deformation in comparison to the control, as found through
scanning and transmission electron microscopy.
RESPONSIBLE EDITOR
Piotr Iwaniuk
CONFLICT OF INTEREST
The authors have declared that no conflict of interests exist.
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