ORIGINAL ARTICLE
 
KEYWORDS
TOPICS
ABSTRACT
It has already been well established that long exposure to low doses of pesticides is linked to consumer risks. So, this study purposed to investigate the amounts of pesticide residues and potential health risks associated with them. The risk assessment was determined by two methods: 1. Pesticide toxicity index (PTI) depending on the maximum residue limit (MRL) to calculate the hazard quotient (HQ); 2. Health risk assessment (HR) using acceptable daily intake (ADI) and estimated daily intake (EDI) to calculate the health index (HI). Pesticide residues were estimated in 176 samples of the most popularly consumed vegetables collected from major retailers and markets in Dakahlia, Egypt (during 2018). There were 111 samples contaminated with pesticide residues (63.1%), of which 29 samples (16.48%) were higher than the maximum residue limits (MRL). Residues of 23 compounds were found in the analyzed samples, of which chlorpyrifos was the most frequent in 33 samples (18.75%); while cypermethrin was the lowest (detected in one sample). According to WHO toxicity classification, 12 of the detected pesticides were moderately hazardous (class II), seven pesticides belonged to class III (slightly hazardous), three compounds were found in class U (unlikely to pose an acute hazard with normal use), while carbofuran is a highly toxic compound (class Ib). Also, the obtained data revealed that, the HI’s for the individual pesticides ranged from 0.0018 to 64.0% of ADI indicates no risk of adverse effects following exposure to the individual pesticides. The cumulative exposure amounts (PTI values) ranged from 1.58 in snake cucumber to 128.44 in potato tubers, indicating that, the combined risk index of pesticide residues was a significant health risk for consumers according to the individual risk index. It can be concluded that there is a need for strict regulation and regular monitoring of pesticide residues in foodstuff for consumers’ health protection.
ACKNOWLEDGEMENTS
The authors are thankful to the Academy of Scientific Research and Technology, Egypt, for funding this project. Also, the authors thank the anonymous reviewers for helpful comments on this manuscript.
FUNDING
This research was a part of the project titled “Prevention Practices for Occupational Workers from Adverse Effects of Pesticides and the Safe Disposal of Expired Compounds” funded by the Academy of Scientific Research and Technology, Egypt during 2016–2018.
RESPONSIBLE EDITOR
Piotr Kaczyński
CONFLICT OF INTEREST
The authors have declared that no conflict of interests exist.
 
REFERENCES (38)
1.
Akoto O., Azuure A.A., Adotey K.D. 2016. Pesticide residues in water, sediment and fish from Tono Reservoir and their health risk implications. SpringerPlus 5: 1849. DOI: https://doi.org/10.1186/s40064....
 
2.
Bajwa U., Sandhu K.S. 2014. Effect of handling and processing on pesticide residues in food – A review. Journal of Food Science and Technology 51: 201–220. DOI: 10.1007/s13197-011-0499-5.
 
3.
Belden J.B., Gilliom R.J., Martin J.D., Lydy M.J. 2007. Relative toxicity and occurrence patterns of pesticide mixtures in streams draining agricultural watersheds dominated by corn and soybean production. Integrated Environmental Assessment and Management 2007 (3): 90–100.
 
4.
Chaikasem S., Roi-et Na. V. 2020. Health risk assessment of pesticide residues in vegetables from river basin area. Applied Environmental Research 42 (2): 46–61. DOI: https://doi.org/10.35762/AER.2....
 
5.
Claeys W.L., Jean-Francois S., Bragard C., Maghuin-Rogister G., Luc P., Schiffers B. 2011. Exposure of several Belgian consumer groups to pesticide residues through fresh fruitand vegetable consumption. Food Control 22 (3–4): 508–516. DOI: doi.org/10.1016/j.foodcont.201....
 
6.
CAC. 1993. Codex Alimentarius Commission. Joint FAO/WHO Food Standards Program, Volume 2, 391 pp.
 
7.
Dragus A., Beldean-Galea M.S., Mihaiescu R., Mihaiescu T., Ristoiu R. 2012. Assessing impacts of triazine pesticides use in agriculture over the well water quality. Environmental Engineering and Management Journal 11: 319–323.
 
8.
EU. 2016. The 2016 European Union report on pesticide residues in food. Scientific report. EFSA Journal 2018. DOI: 10.2903/j.efsa.2018.5348.
 
9.
EU. 2020. European Commission (EU): EU Pesticide Database (Online) Available from: https://ec.europa.eu/food/plan...? Event =pesticideresidue. Current MRL& language = EN&pestResidueId =56. [Accessed 15 August 2020].
 
10.
Fantke P., Gillespie B.W., Juraske R., Jolliet O. 2014. Estimating half-lives for pesticide dissipation from plants. Environmental Science and Technology 48: 8588–8602. DOI: https://doi.org/10.1021/es5004....
 
11.
Fantke P., Juraske R. 2013. Variability of pesticide dissipation half-lives in plants. Environmental Science and Technology 47: 3548–3562. DOI: https://doi.org/10.1021/es3035....
 
12.
Gad Alla S.A., Thabet W.M., Salama E.Y. 2013. Monitoring and risk assessment of pesticide residues in some egyptian vegetables. Middle East Journal of Applied Sciences 3 (4): 216–230.
 
13.
Goumenou M., Tsatsakis A. 2019. Proposing new approaches for the risk characterization of single chemicals and chemical mixture: The source related Hazard Quotient (HQs) and Hazard Index (HIs) and the adversity specific Hazard Index (HIA). Toxicology Reports 6: 632–636. DOI: https://doi.org/10.1016/j.toxr....
 
14.
Hossain M.S., Fakhruddin A.N.M., Alamgir Zaman Chowdhury M., Rahman, M.A., Khorshed Alam M. 2015. Health risk assessment of selected pesticide residues in locally produced vegetables of Bangladesh. International Food Research Journal 22 (1): 110–115.
 
15.
Ibrahim N.M., Eweis E.A., El-Sawi S.AM., Nassar K.R.A. 2018. Monitoring and risk assessment of pesticide residues in some vegetables in Egypt. Middle East Journal of Applied Sciences 8 (2): 669–679.
 
16.
ILNAS-EN 15662:2018. Foods and plant origin – Multimethod for the determination of pesticide residues using GCand LC- based analysis following acetonitrile extraction/partitioning and clean-up by dispersive SPE–Modular QuEChERS method. European Committee for Standardization, Brussels.
 
17.
Kalliora C., Mamoulakis C., Vasilopoulos E., Stamatiades G.A., Kalafati L., Barouni R., Karakousi T., Abdollahi M., Tsatsakis A. 2018. Association of pesticide exposure with human congenital abnormalities. Toxicology and Applied Pharmacology 346: 58–75. DOI: 10.1016/j.taap.2018.03.025.
 
18.
Khan N., Yaqub G., Hafeez T., Tariq M. 2020. Assessment of health risk due to pesticide residues in fruits, vegetables, soil and water. Journal of Chemistry 2020: 1–7. DOI: https://doi.org/10.1155/2020/5....
 
19.
Lehotay S.J., Koka Hiemstra M., Bodegraven P. 2005. Validation of a fast and easy method for the determination of residues from 229 pesticides in fruits and vegetables using gas and liquid chromatography and mass spectrometric detection. Journal of AOAC International 88: 595–614.
 
20.
Mac Loughlin T.M., Leticia Peluso M., Agustina Etchegoyen M., Alonso L.L., Cecilia de Castro M., Cecilia Percudani M., Marino D.J.G. 2018. Pesticide residues in fruits and vegetables of the argentine domestic market: Occurrence and quality. Food Control 2018 (93): 129–138. DOI: https://doi.org/10.1016/j.food....
 
21.
Malhat F., Kasiotis K.M., Shalaby Sh.E.M. 2018. Magnitude of cyantraniliprole residues in tomato following open field application: A prelude to risk assessment. Environmental Monitoring and Assessment 190: 116. DOI: 10.1007/s10661-018-6496-7.
 
22.
Munn M.D., Gilliom R.J., Moran P.W., Nowell L.H. 2006. Pesticide Toxicity Index for Freshwater Aquatic Organisms. 2nd ed., Scientific Investigations Report 2006-5148. Reston, VA. 2006. [Available on: https://pubs.usgs.gov/sir/ 2006/5148/sir_2006-5148].
 
23.
Pathak M.K., Fareed M., Srivastava A.K., Pangtey B.S., Bihari V., Kuddus M., Kesavachandran C. 2013. Seasonal variations in cholinesterase activity, nerve conduction velocity and lung function among sprayers exposed to misture of pesticides. Environmental Science and Pollution Research 20: 7296–7300. DOI: 10.1007/s11356-013-1743-5.
 
24.
Ramadan M.F.A., Abdel-Hamid M.M.A., Altorgoman M.M.F., AlGaramah H.A., Alawi M.A., Shati A.A., Shweeta H.A., Awwad N.S. 2020. Evaluation of pesticide residues in vegetables from Asir Region, Saudi Arabia. Molecules 2020 (25): 205.
 
25.
Seo Y., Cho T., Hong C., Kim M., Cho S., Park W., Hwang I., Kim M. 2013. Monitoring and risk assessment of pesticide residues in commercially dried vegetables. Preventiv Nutrition and Food Science 18 (2): 145–149. DOI: 10.3746/pnf.2013.18.2.145.
 
26.
Shalaby Sh.E.M., Abdou G.Y. 2020. Assessment of pesticide residues in blood samples of agricultural workers in Egypt. Journal of Plant Protection Research 60 (4): 369–376. DOI: https://doi.org/10.24425/jppr.....
 
27.
Shalaby Sh.E.M., Abdou G.Y. 2010. The influence of soil microorganisms and bio- or organic rertilizers on dissipation of some pesticides in soil and potato tubers. Journal of Plant Protection Research 50 (1): 86–92. DOI: 10.2478/v10045-010-0015-3.
 
28.
Shalaby Sh.EM., El-Saadany S., Abo-Eyta A., Abdel-Satar A., Al-Afify A., Abd El-Gleel W. 2018. Levels of pesticide residues in water, soil sediment and fish samples collected from Nile River in Cairo, Egypt. Environmental Forensics 19 (4): 228–238. DOI: 10.1080/15275922.2018.1519735.
 
29.
Silipunyo T., Hongsibsong S., Phalaraksh C., Laoyang S., Kerdnoi T., Patarasiriwong V., Prepamontol T. 2017. Determination of organophosphorus pesticide residues in fruits, vegetables and health risk assessment among consumers in Chiang Mai Province, Northern Thailand. Research Journal of Environmental Toxicology 11: 20–27. DOI: 10.3923/rjet.2017.20.27.
 
30.
Tsatsakis A., Kouretas D., Tzatzarakis M., Stivaktakis P., Tsarouhas K., Golokhvast K., Rakitskii V., Tutelyan V., Hernandez A., Rezaee R. 2017. Simulating real-life exposures to uncover possible risks to human health: a proposed consensus for a novel methodological approach. Human and Experimental Toxicology 36: 554–564. DOI: 10.1177/0960327116681652.
 
31.
USEPA 1998. United States Environmental Protection Agency, Guidelines for Ecological Risk Assessment. EPA/630/R-95/002FApril 1998. Washington DC.
 
32.
Walpole S.C., Prieto-Merino D., Edwards P., Cleland J., Stevens G., Roberts I. 2012. The weight of nations: an estimation of adult human biomass. BMC Public Health 12: 439. DOI: http://dx.doi.org/10.1186/1471....
 
33.
WHO. 2003. World Health Organization. Diet, nutrition and prevention of chronic diseases. Report of a Joint FAO/WHO Expert Consultation, Geneva (WHO Technical Report Series No. 916).
 
34.
WHO. 2009. GEMS/food regional diets. Regional per capita consumption of raw and semi-processed agricultural commodities. [Available on: Internet:http://www.who.int/foodsafety/...] [Accessed: 12 November 2019].
 
35.
WHO. 2019. World Health Organization. The WHO Recommended Classification of Pesticides by Hazard and Guideline to Classification 2019, p 6.
 
36.
WHO/GEMS/FOODS. 2006. GEMS/food regional diets (regional per capita consumption of raw and semi-processed agricultural commodities). [Available on: http://www.who.int/foodsafety/...].
 
37.
Wiles R., Davies K., Campbell C. 1998. Over exposed organophosphate insecticides in children’s food. Environmental Working Group, Washington. [Available on: https://www.ewg.org/research/o...].
 
38.
Wołejko E., Łozowicka B., Kaczyński P. 2014. Pesticide residues in berries and juices and potential risk for consumers. Desalination Water Treatment 52: 3804–3818. DOI: https://doi.org/10.1080/194439....
 
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